Download foobar2000, install the ABX compararator,...then decide for yourself.
Too many will claim FLAC is better, ALAC is better, WAV is better, etc. Test for yourself, try to do a blind test, then DECIDE WHAT'S BEST FOR YOUR EARS. I think you'll notice that most people are not able to tell the difference. In a high end HOME setup it quite possibly will sound better,...maybe.
Me, lossless is for archive purposes, and lossy is for portables.